Product Name: Amoxicillin Soluble Powder
[main ingredients]
Amoxicillin
【Properties】
This product is a white powder.
Pharmacological effect
Amoxicillin is a β-lactam antibiotic with a broad-spectrum antibacterial effect. The antibacterial spectrum and antibacterial activity are basically the same as those of ampicillin. The antibacterial activity against most Gram-positive bacteria is slightly weaker than that of penicillin, which is sensitive to penicillinase, so it is ineffective against penicillin-resistant Staphylococcus aureus. It has a strong effect on Gram-negative bacteria such as Escherichia coli, Proteus, Salmonella, Haemophilus, Brucella and Pasteurella, but these bacteria are prone to drug resistance. Not sensitive to Pseudomonas aeruginosa. Because its absorption in monogastric animals is better than that of ampicillin and the blood concentration is higher, it has a better effect on systemic infection. It is suitable for systemic infections such as respiratory system, urinary system, skin and soft tissue caused by sensitive bacteria.
Pharmacokinetics Amoxicillin is quite stable to gastric acid, and 74% to 92% of monogastric animals are absorbed after oral administration. The contents of the gastrointestinal tract affect the rate of absorption, but do not affect the degree of absorption, so it can be mixed and administered. After oral administration at the same dose, the serum concentration of amoxicillin was 1.5 to 3 times higher than that of ampicillin.
【medicine interactions】
(1) This product is combined with aminoglycosides to increase the concentration of the latter in the bacteria and exhibit synergistic effects.
(2) Fast-acting bacteriostatic agents such as macrolides, tetracyclines and amide alcohols have an interference effect on the bactericidal action of this product, and should not be used together.
[function and use]
--lactam antibiotics. It is used to treat Gram-positive and Gram-negative infections sensitive to amoxicillin in chickens.
